Coenzyme Q10 Best Antioxidant Anti-Ageing Soothing Coenzyme Q10 description Also known as ubiquinone, it is a vitamin-like, fat-soluble substance naturally present in the body. A handful of studies have shown that coenzyme Q10 (CoQ10) may help improve the appearance of signs of ageing.There is also research showing that environmental factors deplete the presence of CoQ10 in the skin. The latest research suggests that topical application of CoQ10 has antioxidant and skin-soothing effects. As such, it is one of many helpful antioxidants for skin, but it is not the only one or the “best.” Related ingredients: Ubiquinone