Comfrey Extract Worst Plant extracts No known benefits Comfrey Extract description Comfrey extract is the extract of a perennial herb. Topical application of comfrey has skin-soothing properties, but it is recommended only for short-term use and only then if you can be sure the amount of pyrrolizidine alkaloids is less than 100 micrograms per application - something that is impossible to determine without sophisticated testing equipment - making comfrey an ingredient to avoid. The alkaloid content means it has the potential to aggravate skin. For more information, please see the entry for _Symphytum Officinale_ Extract. Related ingredients: Symphytum Officinale Extract