DMDM Hydantoin Bad Preservative No known benefits DMDM Hydantoin description DMDM hydantoin is a synthetic, formaldehyde-releasing preservative that has mixed research on its potential to aggravate skin. Despite its connection to formaldehyde, the Cosmetic Ingredient Review Board has confirmed the safety of this preservative in three separate reviews, each spaced several years apart. Related ingredients: Formaldehyde-Releasing Preservative