Escin

Best

Antioxidant

Escin at a glance

  • Main saponin of the horse chestnut tree
  • Exhibits antioxidant properties
  • Could also have topical anti-inflammatory properties
  • Also known as aescin

Escin description

Escin, also called aescin, is the main saponin (a type of carbohydrate) of _Aesculus hippocastanum_, or horse chestnut, a tree native to parts of Europe, Asia, the Middle East, and North America. Like most plant extracts, it exhibits antioxidant properties. Of most interest though to researchers, however, is its potential to mitigate factors that can lead to inflammation. Though this research is primarily linked to oral use, there’s exciting potential for it to have the same benefits when applied topically as well.

Escin references

  • Pharmacology, Toxicology & Pathology, December 2021, ePublication
  • Journal of Basic and Clinical Physiology and Pharmacology, July 2020, ePublication
  • Drug Development Research, November 2019, pages 921-932
  • Drug Design, Development and Therapy, September 2019, pages 3425–3437
  • Chinese Journal of Natural Medicines, February 2018, pages 105-112

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.