Madecassoside

Best

Antioxidant

Madecassoside at a glance

  • Found in Centella asiatica plant
  • Potent antioxidant properties
  • Also has soothing abilities
  • Helps improve the appearance of dark spots

Madecassoside description

Madecassoside is of four principal bioactive compounds in the plant extract _Centella asiatica_. One double-blind study has shown even small amounts of this compound (0.1% in one case) combined with vitamin C have antioxidant benefit when applied to skin, and it serves as an antioxidant in its own right. Studies also show it is non-sensitizing and can help revitalise skin’s surface.

Madecassoside references

  • International Journal of Molecular Medicine, November 2024, pages 1–12
  • Journal of Drug Delivery and Therapeutics, September 2024, pages 151-156
  • Journal of Medicinal Food, December 2023, pages 919-926
  • International Journal of Toxicology, June 2023, pages 5S-22S
  • Journal of Cellular and Molecular Medicine, March 2023, pages 593-608
  • Evidence-Based Complementary and Alternative Medicine, November 2021, pages 1–8
  • Applied Sciences, September 2021, pages 1-29
  • Journal of the Medical Sciences, July 2021, pages 274-289

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.