Palmitoyl Tetrapeptide-10

Good

Peptide

Palmitoyl Tetrapeptide-10 at a glance

  • Synthetic peptide
  • Not widely used in cosmetics
  • Manufacturer claims it improves brightness + smoothness

Palmitoyl Tetrapeptide-10 description

Palmitoyl tetrapeptide-10 is a cosmetic ingredient – a synthetic peptide – obtained through the reaction of palmitic acid and tetrapeptide-10. Lysine, threonine and phenylalanine are the amino acids whose sequence comprises this peptide. At the time of this writing, this peptide isn’t in wide use in cosmetics and there isn’t a breadth of independent research regarding its efficacy in skin care products. Its manufacturer claims palmitoyl tetrapeptide-10 promotes skin brightness and smoothness by speeding up skin’s shedding process. The independent Cosmetic Ingredient Review considers palmitoyl tripeptide-10 a skin conditioning ingredient. Used on its own, the recommended concentration is 0.0006%.

Palmitoyl Tetrapeptide-10 references

  • UL Prospector, Website, Accessed February 2025
  • Journal of Cosmetic Dermatology, December 2024, pages 4,325-4,333

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.