Teprenone

Best

Antioxidant

Teprenone at a glance

  • Has antioxidant properties
  • Also an anti-inflammatory agent
  • Can inhibit melanin synthesis
  • Also called geranylgeranylacetone

Teprenone description

Teprenone, also known as geranylgeranylacetone, is a type of compound known as an acylic polyisoprenoid, a linear rather than a cyclic, ring-shaped molecule. Since 1984, it has been used as a treatment for gastric ulcers in Japan and other Asian countries under the brand name Selbex. In addition to its gastro-protective properties, science has found teprenone useful in a variety of additional applications. Of note is its antioxidant and anti-inflammatory properties, indicating usefulness when it comes to anti-aging. A recent study even found that teprenone has the ability to inhibit melanin synthesis, meaning it could become an effective treatment for skin discolorations caused by the overproduction of melanin. From a skin longevity standpoint, teprenone seems to play a role in reducing multiple intrinsic factors that can cause skin to look prematurely aged, especially from direct exposure to UV light. As such, it may have benefits for restoring a firmer, less lined look and feel to damaged skin. The recommended use level of teprenone in cosmetics is 3% when combined with the emollient caprylic/capric triglyceride.

Teprenone references

  • PubChem.com, Website, Accessed November 2024
  • ScienceDirect.com, Website, Accessed November 2024
  • International Immunopharmacology, June 2024, ePublication
  • Antioxidants, August 2023, pages 1-18
  • Life Sciences, June 2015, pages 51-56 and August 2013, Pages 226-232

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.